![]() ![]() This binding is facilitated by another molecule called dnaC. Two copies of dnaB proteins (helicase) binds to 13 mer repeats.The dna A protein and ATP trigger the opening of 13 mer repeats froming open complex. About 20 molecules of Dna A proteins binds with 9 mer repeats along with ATP which causes DNA to wraps around dnaA protein forming initial complex.Two types of conserved sequences are found at OriC, three repeats of 13 bp (GATRCTNTTNTTTT) and four/five repeats of 9 bp (TTATCCACA) called 13 mer and 9 mer respectively. ![]() In E coli, replication origin is called OriC which consists of 245 base pair and contains DNA sequences that are highly conserved among bacterial replication origin. Termination DNA replication in prokaryotesÄNA replication begins from origin. It proceed from a specific point called originÄ£.The process is called replication in sense that each strand of ds DNA serve as template for reproduction of complementary strand. DNA replication is fundamental process occurring in all living organism to copy their DNA. ![]()
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